Urate Deposition in Man and its Clinical Consequences

One person in four in the industrialized countries suffersfrom hyperuricemia and is therefore at risk of developinggouty arthritis, nephrolithiasis, or any of the otherconsequences of urate deposition.At present, far too little is known about urate depositionand the mechanisms by which it occurs, as well as about itsclinical consequences, which include formation of toph; overthe helix of the ear or in bones close to joints that havenever exhibited an attack, development of bursitis, chronictendo