Signaling in the Heart

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.  The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atheroscle