Paraneoplastic Syndromes

Paraneoplastic syndromes comprise a variety of signs and symptoms that are not directly caused by the primary tumor or its metastases. They may be metabolic, dystrophic or degenerative disorders resulting from remote humoral or hormonal effects, and spontaneously disappear after successful tumor excision or chemo- or radiotherapy. A few years ago, paraneoplastic syndromes were still thought to be rare. Today, we know that a single tumor is capable of producing a variety of hormones and that para