Meningitis and Encephalitis

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae.  The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs,  overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportio