Immunology of Pregnancy 2013

Since a September, 1992, Nature article which read: "Can there be life without LIF?", researchers now realize that the maternal immune system is both a foe (it can reject the conceptus) and a friend (immune cells and molecules are also necessary for successful pregnancy). Leukemia Inhibitory Factor (LIF) when absent, prevents embryo implantation in rodents. From fecundation to parturition, immunity acts as a Janus, required but potentially dangerous. However, the complexity and the diversity of