Hormones and Human Breast Cancer

Seventeen years ago Mr. HAYWARD came to work in the Breast Clinic at Guy's Hospital. At that time the influence of hormones on the progress of breast cancer was appreciated; the prescription of androgens and oestrogens in the treatment of the advanced case was well established, and the operations of adrenalectomy and hypo­ physectomy had recently been introduced. Nevertheless, the prevailing view of the nature of breast cancer was that it was a local malignancy which had to be eradicated before