Development of the Cardiac Conduction System

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat.  Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues.  The cellular and molecular mechanisms that govern development of the PCS are now starting to be under