Blastomycosis

Blastomycosis remains the most enigmatic of human mycotic infections. The enigmas encompass the natural habitat of the etiologic agent, extent of exposure and subclinical infections in endemic areas, distribution of en­ demic foci throughout the world, inconsistency of serologic evaluation of infected patients, and varying response of such patients to standard treat­ ment regimens. In spite of diligent investigations by many competent investigators, we still do not know the ecological niche in