Basic and Clinical Aspects of Helicobacter pylori Infection

A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastro­ intestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a con­ sequence of the results of basic and clinical research in this field. Progress in understanding the pathogenesis of this bacterium has been made by studying H. pylori infection in animal models. More specific diagnostic tools have been devel